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Trichomonas vaginalis, first described by Donn , 1836, for many years has been associated with lesions of the female genital tract. The frequent coexistence of trichomonal cervicitis and cervical cancer has caused much speculation concerning a possible etiologic relationship. It is our purpose for this study to evaluate the relationship between trichomonas-induced inflammatory change and carcinogenesis in the uterine cervix. From January 1978 through December 1978, colposcopic examinations were taken in a series of 346 patients. Among them, we selected the trichomonal cervicitis, 30 cases, who were taken colposcopic examination and biopsy for the evaluation of the trichomonal cervicitis and its relationship to cervical precancerous lesion. The results were as follows; 1. The presence of large areas of "double-crested capillaries" is a very strong indication of active trichomonal infection. 2. The trichomonal cervicitis is found in 30 patients; 15(50.0%) of whom are cases of class Ⅳ colposcopic classification, and 2 of class Ⅴ that are precancerous lesion. 3. Increased vascularity of the squamous epithelium appeared to be by far the most sensitive index of structural alterations associated with trichomonas. Intracellular vacuolization, squamous metaplasia of endocervical lining cell and basal cell hyperplasia were also noted. 4. There is evidently and association between cervical carcinoma and infestation with Trichomonas vaginalis, although a direct causal relationship is unproved.
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